GHK-Cu cream

GHK-Cu Cream

Prescription-strength GHK-Cu in a topical cream, applied directly to areas of visible aging. Supports firmness, texture, and tone on the face, neck, and hands.

  • Applied topically, once daily
  • Studied for collagen and elastin production
  • Compounded at a US pharmacy at prescription strength

FormSame medication. Pick how you take it.

Select your supply

Billed every 90 days, cancel anytime.

  • Prescribed by a US-licensed provider
  • Compounded at a US 503(a) pharmacy
  • Shipped cold, ready to use
  • HSA / FSA eligible
Safety information

Side effects are possible with any medication. Read the full safety information for GHK-Cu and discuss all medications with your provider.

Compounded medication. Compounded products are not FDA approved. Optera provides compounded GHK-Cu from US-licensed 503(a) pharmacies only.

Common side effects. Mild redness, tingling, or dryness where applied, most often in the first weeks. Individual responses vary. Tell your provider about any side effect you think is related to GHK-Cu.

Talk to your provider first. If you are pregnant, breastfeeding, or planning to become pregnant, if you have a copper-related condition such as Wilson's disease, or if you use prescription retinoids or acids on the same areas.

When to stop. Stop and contact your care team if you experience a severe reaction. For a medical emergency, call 911.

Prescription treatments are dispensed only when clinically appropriate after provider review. Compounded medications are not FDA approved.

Round Out Your Plan

Commonly prescribed together. Add a second product for $60 off, or three for $120 off.

What Is GHK-Cu?

(glycyl-L-histidyl-L-lysine copper complex)

GHK-Cu is a small peptide bound to copper that your body makes on its own. It is found in blood, saliva, and urine, and it acts as a signal that tells skin cells to build collagen and elastin and to repair damage. Research shows GHK-Cu levels fall sharply between your twenties and your sixties, and lower levels have been linked to slower skin repair and loss of firmness.

GHK-Cu works as a signaling molecule. In research, it has been shown to switch on genes involved in collagen and elastin production and to switch down genes tied to inflammation and tissue breakdown. Copper is part of the mechanism: the enzyme that cross-links new collagen fibers depends on it.

GHK-Cu levels decline with age

GHK-Cu levels203040506070

Illustrative only. Individual levels and results vary.

Firmness

May support firmer-looking skin on the face and neck.

Texture

May improve skin smoothness and texture.

Tone

May support a more even skin tone.

Targeted Application

Applied exactly where it's needed.

Individual results vary and are not guaranteed.

How GHK-Cu Cream Works

What GHK-Cu does in the skin over time.

Day 1

GHK-Cu activates genes involved in collagen production and tissue repair.

30 Days

Skin may feel smoother and more hydrated.

3 Months

Increased collagen and elastin may improve firmness and texture.

6 Months

Fine lines may soften and tone may look more even.

1 Year and Beyond

Continued support as the body's own GHK-Cu declines with age.

Timeline reflects the general mechanism and published research. Individual results vary and are not guaranteed.

How Optera Works

100% online care, personalized dosing, and treatment delivered to your door.

01

Build your protocol and share your health history.

Optera intake on a tablet
02

Our providers review and prescribe if it's right for you.

Patient messaging an Optera provider on a tablet
03

Compounded and shipped cold to your door.

Optera box delivered

Learn More About GHK-Cu Cream

Ready When You Are

Answer a few questions and a licensed provider will tell you whether this is a fit.